Prostate cancer and analysis
April 2nd, 2008 Guage
Prostate cancer and analysis
The Prostate cancer is senior citizen’s vigorous sickness, occurs most in 60 year-old above masculine senior citizen.
In areas and so on Europe and US, the Prostate cancer’s formation rate is extremely high, is situated all masculine cancer disease incidence rate first or second. For example, a US development facility in the masculine senior citizen’s common autopsy discovered to 50 years old above that the Prostate cancer’s disease incidence rate is 158%, moreover is the age is bigger, the disease incidence rate is higher; And, above 80 years old the man competes has 2/3 has the prostate gland cancer. However, these people are having the clinical symptoms before death only then a small part, the majority of life does not have any ill. According to the statistics of expert, the US 1981 Prostate cancer clinical disease incidence rate accounted for the gross population the proportion to have 69 people for average every 100,000 people, the mortality rate has 18.8 people for every 100,000 people in; In the complete cancer mortality rate, the Prostate cancer’s mortality rate accounts for about 10%.
The Prostate cancer must be lower than the European and American countries obviously in China’s disease incidence rate and the mortality rate. If in 1984 Beijing regional statistics, the Prostate cancer in 100,000 person of disease incidence rates were 0.75%, for the US 1/90; The mortality rate is 0.59%, for the US 1/1800 in the last few years, although our country’s Prostate cancer morbidity number goes up, achieves in the average 100,000 people to have 1.3 people, but the US was still higher than our country 50 times. Regarding this kind of national sector disease incidence rate disparate disparity’s reason, also is not too at present clear. But has a point to be possible to affirm that local and the race difference has the obvious influence to the disease incidence rate. For example, with in the US, the black disease incidence rate is higher than two times compared to the Caucasian, is higher than 6 times compared to the Chinese American, this has prompted the kind is the gene is affecting the Prostate cancer’s formation rate. Next, the living conditions also affect the morbidity situation. A Chinese life lives in China, suffers from the Prostate cancer’s possibility is very small; But if he migrates to the US, contracted the Prostate cancer’s possibility greatly to increase, moreover correspondingly increased along with the settling down time’s extension. In addition, even if in identical area, habits and customs change, also will affect the disease incidence rate. The Japanese original Prostate cancer disease incidence rate and China are similar, but in the recent 20 years, the living standard enhances unceasingly, the life style westernizes gradually, the Prostate cancer’s disease incidence rate also obviously increased, now the Japanese Prostate cancer’s disease incidence rate enhanced to the European and American countries 1/10-1/15. This is also precisely to a China’s warning, for these years, our country people’s living standard also enhanced many, the westernization life style already appeared in some person’s daily life, the Prostate cancer’s disease incidence rate has the possibility to enhance correspondingly. According to Shanghai’s statistics, the Prostate cancer’s disease incidence rate increased above now 50% compared to the 60s, and has the tendency which increases rapidly. Therefore, formerly that kind thought that the Prostate cancer and our Chinese big relations’ viewpoint already had not been obsolete, in the old age male, the vigilant Prostate cancer’s occurrence is necessary.
At present, is not explicit to the Prostate cancer’s cause of disease, is only discovered from each kind of clinical picture, in vivo sex hormone level’s change has the relations to the Prostate cancer’s growth. In these, because all sorts of reasons have made the two-sided testicle excision in the young people time, or the original two-sided testicle maldevelopment in the human, will always not have the prostate gland cancer. Many Prostate cancer patient after excision two-sided testicle, because in the blood the androgen level’s drop, the tumor may be under obvious suppression. Present’s understanding is, the androgen possibly stimulates the prostate gland epidermis the growth, for has occurred becomes malignant the cell to provide the material base, but it will not cause the prostate gland cancer. What because is the true pathogenesis? It is estimated that certain foods metabolism ingredient which produces in vivo concerns with the diet.
Moreover, but also many person issue of concern, is in the Chinese the common prostate gland proliferation or the chronic prostatitis, to be whether influential to the Prostate cancer’s occurrence? At present, concerns this aspect research not to draw the explicit conclusion. Looked from the tumor cause of disease’s inflammation theory that the chronic inflammation’s stimulation is possibly one which of causes cancer occurs, it may create tissue cell’s heteromorphism change. However, in the prostate gland cancer, the inflammation theory’s function is not clear. Our opinion is, if has the chronic prostatitis, sooner treat to well, like this not only may remove the illness which the inflammation itself brings, also reduced one kind of possibility pathogenic factor, why not? Relate whether there is to the prostate gland proliferation and does the Prostate cancer in the morbidity study, had many research, the opinion is inconsistent. Some people discovered that in the prostate gland proliferation patient, the Prostate cancer’s disease incidence rate and the mortality rate must not have the prostate gland proliferation person to be higher than; In nearly half of prostate gland cancers organize, discovered that is accompanied by the varying degree the proliferative change. In the US, some people discovered that undergoes the surgery to excise in prostate gland’s prostate gland proliferation patient, has nearly 1/4 makes the pathology inspection discovery to be accompanied by the prostate gland cancer, therefore proposed that before the prostate gland proliferation may regard as the cancer, the pathological change organizes, before and regards as the proliferation process the cancer, changes the process. But, the majority scholars opposed that this opinion, thought between these two kind of pathological changes the obvious relations, they have not been same in prostate gland’s occurrence spot. The Prostate cancer most occurs in the prostate gland later generations; But the prostate gland proliferation much occurs in the lateral lobe and the middle period, ever does not occur in the later generations. However, also had one new formulation for these years, was called the prostate gland proliferation accidental cancer, referred to cancer which specially discovered in the prostate gland proliferation surgery specimen. In the European and American countries, the accidental cancer occupies the prostate gland proliferation patient 120%; In our country, approximately about 20%. The local difference is not very big. Is develops regarding this kind of accidental cancer by the prostate gland non-typical proliferation; Alone develops, does not have what relations with the proliferation? Is not too also clear. Perhaps, the accidental carcinogenesis rate and European and American countries’ close, was reflecting the Prostate cancer in China’s increase, must arouse vigilance. Specially these were the patient who the prostate gland excised, the specimen must certainly deliver make the pathology inspection, in order to avoid omitted the prostate gland proliferation accidental cancer’s diagnosis. The prostate gland is one kind of gland organization, the Prostate cancer also most sees by the adenocarcinoma, approximately composes 95%; Other has divides and hyphenates a word at the end the epithelioma, the squamose epithelioma, and so on. The prostate gland adenocarcinoma may divide into the high split up cancer and the low split up cancer two kinds, splits up cancer’s cell differentiation to be good high, the malignant degree is low; Because the low split up cancer the cell differentiation bad, the malignant degree is extremely high, presents the shift easily in the early time. Usually, the early Prostate cancer is very small, limits in the gland later generations, also does not have what symptom, is very difficult to discover; The later cancer may appear ties the nodular to increase, to increase, spreads in the prostate gland periphery near involucrum place organization quality of material is very hard, sometimes also expands to the entire gland, and penetrates the involucrum, encroaches to the neighbor organization organ, or to distant place lung, liver, brain and so on place shift. Then, what way shift is the Prostate cancer cell through? This with other cancers is similar, namely has direct spread, the lymph vessel shift and the blood line shifts three kinds. Generally, the direct spread first occurs, many Prostate cancer patient is precisely because after cancer encroached upon was close to prostate gland’s seminal vesicle, the urinary bladder, the urethra and so on to organize the organ, when has caused corresponding symptoms and so on blood essence, hematuria or urination difficulty, only then arrived at the hospital to carry on the inspection treatment. However, the lymph vessel and a blood line of shift also by no means occurs in the tumor later period, sometimes prostate gland partial cancer has not encroached upon the involucrum, the patient also does not have any ill symptom, already had on the skeleton, the lung, the collar bone the lymph node and so on place the shift cancer stove, and has many first has the bone to shift. Later, when the inspection will seek for the primary cancer, only then has discovered the prostate gland cancer.
On clinical, doctor frequently based on the Prostate cancer infringement’s degree and the proliferation scope, divides into it four issues:
The first issue (A time), approximately composes about Prostate cancer’s 10%. Cancer limits in the front row glandular tissue, on clinical does not have the symptom, is only discovers cancer in the postmortem examination or in the prostate gland specimen pathology inspection, this kind of cancer belongs to latent much, the malignant degree is very low, patient’s life and the normal contemporaries are similar; However, it may also develop other various issue.
The second issue (the B time), approximately composes the Prostate cancer 125%. Cancer only limits in the front row glandular tissue, the rectum refers to examines may trace, the ultrasound or the CT inspection may also discover, generally does not have the lymph vessel shift, the blood serum acid phosphatase not to be high.
The third issue (C time), approximately 40% Prostate cancer when finding out belongs to the third issue. Cancer already encroached to the prostate gland involucrum outside, the partial lymph node also has the shift, but still did not have the distant place shift, the blood serum acid phosphatase starts to advance.
The fourth issue (the D time), 40% patients belong to the fourth issue. Each kind of inspection confirmed that the distant place shifts the cancer stove, like the lung, the liver, the brain, the bone road and so on place, the blood serum acid phosphatase elevates obviously.
Should point out that various issue of Prostate cancer’s development not necessarily is carries on according to the first issue to the fourth issue of this kind of kind of order, may present the caper-like development, may also not develop for a long time. For example, the first issue of cancer may pause for a long time in the first issue, may also transfer third or the fourth issue directly.
This kind on clinical is by stages very important, not only relates the therapeutic schedule the choice, but also has obvious contacting with the prognosis quality. Generally speaking, the first issue of second issue of patient, so long as treats is prompt and is appropriate, the prognosis is favorable, 5 year survival percentage may above 80%; A third issue of patient’s five year survival percentage is about 60%; But the fourth issue of patient adopts many kinds of methods of treatment freely, also has 25% 5 year survival percentages.
In brief, the Prostate cancer’s development receives many kinds of factors the influences, the difference is very big. In China, this is one kind is being at the ascent stage disease, disease incidence rate in the last few years increases is very rapid, has brought to medical affairs’ attention. As a masculine adult, some understandings, enhance the vigilance which prevents disease to be necessary, strive for the early discovery immediate cure are regarding this very important.
Related Posts
Entry Filed under: Prostate Cancer
Leave a Comment
Some HTML allowed:
<a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>
Trackback this post | Subscribe to comments via RSS Feed
. 