Laboratory improve lymph nodes residual bladder cancer screening

July 7th, 2007 Guage

Expected results suggest that in a radical cystectomy after inspection peripheral bladder and lymph node status of the new technologies may help to identify with adjuvant chemotherapy interests of the patients.   University of Virginia Health Science Center (University of Virginia Heal th Sciences Center) Danxiao more Risku (Dan Theodoresc u), and Dr. colleagues use RT-PCR (reverse transcription - polymerase chain reaction) analysis of the lymph nodes uropla kin II gene (bladder tissue-specific). Each bladder surface samples collected 5, and “in any of bladder tumors may touch on the surface of the bladder collecting specimens of similar size,” from the large lymph nodes or suspicious clinical highest lymph node specimens were collected.

    Researchers at the recent “Clinical Cancer Research” (Clinical Cancer Research ) issued a report saying, 35% of the bladder peripheral tissues and lymph nodes 37% of bladder II gene as a positive. In eight clinical patients with superficial disease, four were peripheral tissue positive; In 19 patients myometrial invasion, 53% peripheral tissue positive, 50% positive lymph nodes.

    Theodore Lane Shikuboshi discovered, such inspection “simple, fast and safe and no incidence of operative time and influential. ” 4 biopsy for patients with a negative judgment of such inspection positive, Pathological examination of all the lymph nodes are positive RT-PCR-positive. Theodore Lane Shikuboshi said that if such checks have been tested will be the “tumor stage, a big step forward,” “through early detection, without time-consuming to observe which patients will relapse.”

   Participate in this new screening test in patients who have reached 75% Theodore Lane Shikuboshi others will observe this RT-PCR-positive patients, and whether the outcome of disease recurrence associated.

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Entry Filed under: Carcinoma of urinary bladder

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