Cancer of the pancreas’s primary hazard factor is
April 7th, 2008 Guage
The research confirmed that smoker’s risk is proportional with its smoking degree. To stops smoking for 10 years to 15 year person, its risk and the life-long smoker are not close. Attracts the cigar, the cigarette, the tobacco pipe and the mastication tobacco does not have the difference in the risky aspect. To cancer of the pancreas’s physiographic region distributed research, like to transplant’s research, explains the environmental factor fully, like diet carcinogenesis. The animal experimentation certificate high fat diet and cancer of the pancreas’s development concerns. Other like meats and the high fever card diet, specially the high carbohydrate, the milk product and sea food are also the related factors. But in the diet structure the high textile fiber, the fruit and green goods’ crowd contracts the cancer of the pancreas to be few. Although drinks the caffeine ethyl alcohol class drink to consider that is the hazard factor which grows, but also has many research not to support this viewpoint.
Similarly, many research do not support between diabetes and cancer of the pancreas’s relevance, although has some forward-looking research demonstration diabetic patient to contract cancer of the pancreas’s risk compared to other people of high 4 times. In recent years the people discovered at the cancer of the pancreas confirmed previous several months often have diabetes outbreak, this discovery possible to remind doctors to need to consider the early cancer of the pancreas’s possibility to the non-diabetes family history middle-aged patient.
With the cancer of the pancreas related occupation is with the chemical substance and the metallic contact work, some researchers thought that in the male which works with the benzene related factory in has with Beta - the naphtyylamine contracts cancer of the pancreas’s high-risk danger.
Cancer of the pancreas’s hereditary factors not yet explicitly were confirmed that but also has the report which the family is taken bad. Near future research thought that in the close relative has the malignant pancreatic neoplasm to be sick the risk to be high.
40 year-old following person contracts the cancer of the pancreas to be extremely few, the sick age is equally 63 years old, the male slightly is higher than the female. Cancer of the pancreas’s mortality rate is nearly consistent with the disease incidence rate, 5 year survival rate is very low, and nearly performs the surgery to treat. Has not accepted the treatment the cancer of the pancreas patient’s survival contract 4 months, accept the patient who the by-pass operation treats to survive contract for 7 months, after excising the surgery, the patient can survive generally for 16 months. According to the newest statistics, 20% patient lifetime are 1 year, 3% patient lifetime are 5 years.
The rodent cancer of the pancreas model which with the big mouse (diazonium acetyl serine), the Syrian hamster (the N- nitroso group pair [2- oxygen third alkyl] amine or amine BOP) as well as the guinea pig (methyl nitroso group urea) duplicates has succeeded. The nitroso group compound is to the rodent most effective careinogen. In food may promote including the massive saturated fat to test the big mouse to form the cancer. The cholecystokinin (CCK) or its synonym frog skin shrinks the gallbladder peptide (cerulein) to be possible to stimulate the experimental animal in vivo exocrine pancreatic gland growth.
The extrapolation is precisely possibly because of the CCK release, therefore in the diet richly may urge the big mouse including the soy flour and the trypsin inhibitor to form the cancer. CCK and the intestines press the pancreatic juice peptide to be possible to stimulate the carcinogen together to cause the cancer of the pancreas. Recent experiment one kind of man-made CCK acceptor antagonist compound before the pancreatic gland new biology forms pours into big mouse in vivo, the certificate may prevent the diazonium acetyl serine the function. However, this kind of antagonist compound must further study in the clinical utilization. The Luo river cuts down his sandbank (Lovastatin) - the - one kind to lower the cholesterol the medicine, may suppress cancer of the pancreas’s growth in vitro experiment.
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Entry Filed under: Pancreatic cancer
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