“Bones” radical esophageal cancer surgery
August 18th, 2007 Guage
Louvain Medical School in Brussels, Belgium Jean-Marie Collard and colleagues studied the “skeleton” esophageal cancer patients after radical surgery for the long-term prognosis.
“Bones” esophageal cancer is radical surgery, esophageal tissues around with esophageal en bloc, including local and regional lymph node tissue, unresectable esophageal around the anatomical structure “of bones.” Patients with esophageal cancer right now whether such an expansion surgery also controversial.
They tried to 324 patients purposes’ skeleton, ‘radical esophageal cancer surgery. Using right chest (208), the diaphragm (39) or left chest into the road (77) removal of the esophagus; All of the patients were on the trip, which includes the abdomen and under the mediastinal lymph node dissection; In addition, the road into the right chest with lymphadenectomy extension of the previous mediastinum, which reached 17 patients with carotid Ministry level. If not completed under a radical esophageal cancer surgery, is used along the esophageal wall resection of the esophagus. According to the development process of tumor resection integrity, depth of invasion esophageal wall and lymph nodes to determine the scope of violations.
324 patients with 5-year survival rate of 35%, hospital mortality rate of 5%. Of these, 117 tumors confined to the wall with five-year survival rate of 64%, and 207 violations of esophageal tumors or in patients with surgical margins of 19% (P <0.0001), the total number of cases by 12%.324 patients with 235 people successfully implemented the “skeleton” radical esophageal cancer surgery, after their five-year overall survival was 49%, with squamous cell carcinoma of the 5-year survival rate was 49%, 47% adenocarcinoma (P = 0.4599); Tumor confined within walls 64%, and violations of esophageal tumors outside the organizers of 34% (P <0.0001); less than five lymph node metastases were 43%, 5 or more lymph node metastases in 11% (P <0.0001).
The results showed that when the tumor violations esophageal tissue but can be removed, ’skeleton,’ esophageal cancer surgery can cure one third of patients with esophageal cancer after achieving long-term survival. They accounted for the overall implementation of esophageal cancer patients with 12% of the total violations of esophageal cancer surgery or in patients with a total margin of 19%.
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