Before the FDG-PET appraisal esophagus cancer technique, is auxiliary the chemotherapy effect to surpass CT and in the mirror supersonic
April 30th, 2008 Guage
Dutch Amsterdam University’s Westerterp and so on after systematic characteristic evaluation study believed that before 18F- the fluorine deaeration glucose positive electron emitter level image formation (FDG-PET) inspection method is one kind has the prospect not to create the appraisal esophagus cancer technique, to be auxiliary the chemotherapy effect the method. [Radiology 2005,236(3):841]
This systematic review research from MEDLINE, EMBASE and in the Cochrane database retrieves the related research paper, carries on the independent appraisal by 2 valuers to each research methodology’s quality. Uses the receiver to operate the characteristic curve (ROC) analysis to carry on the summary and the comparison to 3 kind of inspection method diagnosis accuracy.
Altogether has 4 item of CT related research, 13 item in mirror supersonic (US) related research and 7 item of FDG-PET related research meet standards is selected. Each research methodology quality grading maximum proportion in 15%~100% scopes. Some 3 item of CT related research, 4 item in mirror US related research and 4 item of FDG-PET related research may carry on the ROC analysis. The computation sensitivity and the specificity biggest intersection value, CT is 54%, in mirror US is 86%, FGD-PET is 85%. The CT inspection accuracy is lower than FDG-PET(P<0.006) and in mirror US (P< 0.003), the latter both’s accuracy is close. In all patients, the CT inspection is feasible, but in the mirror US inspection is unable in 6% patients to execute, the FDG-PET inspection is unable to execute the proportion to be lower than 1%.
The researcher believed when the appraisal esophagus cancer patient is auxiliary the chemotherapy alleviation situation before the technique, the CT inspection accuracy is bad, but in mirror US and the FDG-PET accuracy is close, and is high, but in mirror US cannot be suitable after all chemotherapies and the radiotherapy patient. Before looking like FDG-PET is the hopeful esophagus cancer technique, is auxiliary the chemotherapy not to create the appraisal method.
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